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Panax ginseng

Panax Ginseng Blood Sugar Research: How Much Root Is in a Sugar Defender Dropper, and What Trials Found

Quick answer

Panax ginseng blood sugar trials show a small effect: 16 trials found fasting glucose about 5.6 mg/dL lower, with no A1C change. In Sugar Defender, ginseng root extract is 12th of 22 in a 200 mg blend, so 1 mL holds at most 17 mg. Trials used about 100 mg to 20 g a day.

Written by the Sugar Defender label deskUpdated

The plant01

What is Panax ginseng?

Panax ginseng is a slow-growing plant with a pale, forked root. It is also called Asian or Korean ginseng.

The root holds compounds called ginsenosides. Extracts are often sold by their ginsenoside content.

Sugar Defender's panel lists "Panax Ginseng Root Extract". It gives no ginsenoside figure, no extract ratio and no amount.

Not the same as eleuthero

The blend also has eleuthero, sold as "Siberian ginseng". It is a different genus with thinner research.

Whole pale ginseng roots lying on a wooden board
Brand photo of ginseng roots. The label lists the root extract, amount not printed.

Label math02

How much Panax ginseng is in one dropper?

At most about 17 mg. Ginseng is 12th of 22 in the 200 mg blend, and 200 divided by 12 is about 17.

Blend ingredients are listed from most to least by weight (21 CFR 101.36 (eCFR)). So eleven lines weigh at least as much as ginseng, and twelve equal shares would be 17 mg each.

An even split gives about 9 mg. Ten more lines sit below ginseng, so its real share could be smaller still.

Panax ginseng per 1 mL serving next to the doses used in glucose trials
SourcePer dayCompared with 100 mg
Even split of the blendAbout 9 mgAbout 9%
Label-order ceiling (place 12)At most 17 mgAt most 17%
Lowest dose in the 16 trials (Shishtar et al., PLoS One 2014)About 100 mg100%
Highest dose in the 16 trials (Shishtar et al., PLoS One 2014)20 g200 times more

Glucose03

What does research say about Panax ginseng and blood sugar?

The research is mixed. A pooled review of 16 trials found a modest fasting-glucose drop of about 5.6 mg/dL, and no clear effect on A1C or fasting insulin (Shishtar et al., PLoS One 2014).

Those 16 trials had 770 people, and results varied a lot from study to study (Shishtar et al., PLoS One 2014).

NCCIH calls the ginseng and diabetes research inconclusive and conflicting. It also notes a 2022 review of 20 studies that found better fasting glucose (NCCIH, Asian Ginseng).

The bars compare a dropper's share with research doses.

  • Chromium

    0.3% of the low end at 1 mL
    1 mL, the label dose0.7 mcg
    200-1,000 mcg a day in glucose studies200-1,000 mcg

    Printed on the label: 0.7 mcg per mL. (NIH ODS, Chromium)

  • Gymnema

    4.5% of the low end at 1 mL (even split)
    1 mL, the label dose, even split9.1 mg
    1 mL, label-order ceiling (place 8)25 mg
    200-400 mg a day of extract200-400 mg

    Not printed: #8 in a 200 mg blend of 22. (Drugs.com, Gymnema monograph)

  • African mango

    3.0% of the low end at 1 mL (even split)
    1 mL, the label dose, even split9.1 mg
    1 mL, label-order ceiling (place 4)50 mg
    300 mg a day (150 mg twice)300 mg

    Not printed: #4 in a 200 mg blend of 22. (NIH ODS, Dietary Supplements for Weight Loss)

  • Panax ginseng

    9.1% of the low end at 1 mL (even split)
    1 mL, the label dose, even split9.1 mg
    1 mL, label-order ceiling (place 12)17 mg
    From about 100 mg a day (up to 20 g)100 mg

    Not printed: #12 in a 200 mg blend of 22. (Shishtar et al., PLoS One 2014)

  • Green tea

    6.4% of the low end at 1 mL (even split)
    1 mL, the label dose, even split9.1 mg
    1 mL, label-order ceiling (place 7)29 mg
    141-1,207 mg catechins a day141-1,207 mg

    Not printed: #7 in a 200 mg blend of 22. (NIH ODS, Dietary Supplements for Weight Loss)

Red bars: what 1 mL, the label dose, can hold. The label prints just one amount, for chromium; for blend ingredients we show an even split (200 mg / 22, about 9 mg per mL) and the most the label order allows. Gold bars show the daily amount of that one ingredient in studies, and the light extension shows a range. Even the ceilings fall short of the studied doses.

In context04

How big is a 5.6 mg/dL drop in fasting glucose?

Small. Fasting glucose of 100 to 125 mg/dL counts as prediabetes, so 5.6 points is a fraction of that band (NIDDK, Diabetes & Prediabetes Tests).

A1C is the longer view, a two-to-three-month average. The ginseng trials did not move it (Shishtar et al., PLoS One 2014). That is why the effect, where seen, is called modest.

01

Example only

A fasting reading of 112 mg/dL minus 5.6 is about 106. That is still in the prediabetes range.

02

Higher doses

That average came from at least 100 mg a day. A dropper holds at most 17 mg.

03

Not a treatment

NCCIH says herbs such as ginseng have not proven benefit for diabetes (NCCIH, Diabetes and Dietary Supplements).

Read what each range means on normal blood sugar levels.

Safety05

What are the side effects of Panax ginseng?

Insomnia is the most common Panax ginseng side effect, says NCCIH. It may also interfere with blood clotting and interact with some medicines (NCCIH, Asian Ginseng).

NCCIH adds that ginseng might push blood sugar down. So it asks people with diabetes to talk with a provider first (NCCIH, Asian Ginseng).

On insulin or a sulfonylurea, a low is the risk to watch. Shakiness, hunger, dizziness and a fast heartbeat are common signs (NIDDK, Low Blood Glucose).

Keep taking prescribed medicine

Do not cut or skip a diabetes medicine because you added ginseng drops. Bring the full label to your doctor or pharmacist.

  • Blood thinners: ask first, since ginseng may affect clotting
  • Pregnancy: NCCIH says ginseng may be unsafe
  • Sleep: take it earlier in the day if you notice insomnia (our suggestion)

More on supplements and diabetes medication.

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Sales claim06

Is the ginseng claim on the sales page fair?

Only in part. The sales page says ginseng "Supports Healthy Blood Glucose" (Sugar Defender sales page). The trials used far more root than a dropper holds.

A fair line: ginseng alone, at 100 mg a day or more, nudged fasting glucose a little. A1C did not change. A 17 mg share of a mixed blend is another thing.

No trial of the drops

Sugar Defender itself has not been tested. Ginseng results belong to ginseng studies.

Profile07

What does the Panax ginseng label profile show?

The profile puts the panel's ginseng line beside the research dose, evidence grade and main caution.

Panax ginseng in Sugar Defender, from the label to the research. Source list: (NCCIH, Asian Ginseng) (Shishtar et al., PLoS One 2014)
Name on the labelPanax Ginseng Root Extract
What it isAsian ginseng root
Place on the label12 of 22 in the 200 mg proprietary blend
Amount per mL (1 dropper)Not listed; #12 of 22 in the 200 mg blend, so at most 17 mg per mL
Amount used in researchAbout 100 mg to 20 g
Strength of evidenceModest drop in fasting glucose; no A1C effect
Marketed or traditional useStudied for glucose control
Main cautionMay lower blood sugar; may affect blood thinners; insomnia.

Other lines08

Which other Sugar Defender ingredients have glucose research?

FAQ09

Panax ginseng questions, answered

Does Korean ginseng lower A1C?

No clear effect has been shown. A review of 16 trials found that ginseng did not significantly change A1C or fasting insulin, though fasting glucose fell by about 5.6 mg/dL on average (Shishtar et al., PLoS One 2014). A1C reflects about three months, so it is the stricter test of any real change.

What are ginsenosides?

Ginsenosides are the compounds in Panax ginseng root that researchers study most. Extracts are often standardized to a ginsenoside percentage. Sugar Defender's label prints no ginsenoside content and no ginseng amount, only its place as 12th of 22 in the blend, so the dose cannot be checked.

Is Panax ginseng the same as Siberian ginseng?

No. Panax ginseng is Asian or Korean ginseng. Siberian ginseng is eleuthero, a different plant with its own, thinner research. Sugar Defender's blend contains both: eleuthero root is 5th and Panax ginseng root is 12th of 22, with no amounts printed.

Can ginseng cause low blood sugar with diabetes medicine?

It might add to them. NCCIH says ginseng might push blood sugar down and asks people with diabetes to talk to a provider first (NCCIH, Asian Ginseng). Lows are most likely with insulin or a sulfonylurea (NIDDK, Low Blood Glucose). Tell your care team before adding any ginseng product, and keep a meter log.

Is the ginseng in Sugar Defender enough to matter?

Probably not on its own. Trials in the main review gave about 100 mg to 20 g a day (Shishtar et al., PLoS One 2014), while a 1 mL serving holds at most 17 mg and about 9 mg on an even split. The label hides the real amount, so nobody outside the maker can say.

Does Panax ginseng cause insomnia?

It can. NCCIH lists insomnia as the most common side effect of Asian ginseng (NCCIH, Asian Ginseng). Sugar Defender also contains guarana and green tea, which bring caffeine. If sleep suffers, an earlier time of day is a sensible habit, and a doctor can help sort out the cause.

Who wrote this10

Written and reviewed by

Written byThe Sugar Defender label deskIsugardefender, Sugar Defender U.S. shop

Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.

Medically reviewed byDr. Andres Palacio, MD, PhysicianRole: Medical reviewerReview date: October 19, 2026

Last updated . Read our editorial standards and how we check reviews. This website is run by Isugardefender, a Sugar Defender U.S. shop, not by the manufacturer or the distributor. We earn money when you buy through our order links.

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