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Sugar Defender Kidney and Liver Safety: What the Sources Say

Quick answer

Sugar Defender kidney and liver safety has not been tested, and the label prints no organ warning. Sources do flag a few blend ingredients: rare liver injury with green tea extract, and one kidney failure case with African mango. Anyone with kidney or liver disease should ask their clinician before use.

Written by the Sugar Defender label deskUpdated · 4 min read

Two Sugar Defender amber dropper bottles
Two bottles. The label carries no kidney or liver warning, and no organ safety test is published.

The gap01

Has Sugar Defender been tested for kidney or liver safety?

No. We found no organ safety study of the finished drops and no published lab report for the product.

The label asks you to consult a physician if you take other medication, and says nothing about kidney or liver conditions. Silence on a label is not a safety statement; FDA does not approve supplements before sale (FDA, Using Dietary Supplements).

Ingredient flags02

Which ingredients do sources flag for the liver or kidneys?

Green tea and African mango are the two with organ-specific notes. Others raise related questions through blood pressure.

Organ-related notes in cited sources
IngredientWhat the source says
Green teaLiver injury is uncommon but reported, mostly with extracts in tablets or capsules (NCCIH, Green Tea)
African mangoOne case of kidney failure needing dialysis was reported (MSKCC, Irvingia gabonensis (African mango))
Licorice compoundGlycyrrhizin can cause irregular heartbeat and may affect people with high blood pressure (NCCIH, Licorice Root)
Raspberry ketonesHuman data only come from multi-ingredient products (OPSS (DoD), Raspberry Ketone)

These are single reports and small studies, not findings about these drops. Blend amounts are hidden, with an even split near 9 mg per mL (21 CFR 101.36 (eCFR)).

Your situation03

Does your own situation change the question?

It can, because a supplement is one more thing for your clinician to weigh against your health history.

1. Do you take insulin, a sulfonylurea (such as glipizide) or any other prescription medicine?
2. Are you pregnant or nursing, or under 18?
3. Are you sensitive to caffeine, or do you take a stimulant?
4. Is there a dog in your home?
5. Have you had a low blood sugar episode (shaky, sweaty, confused) in the past few months?
Answer all fiveYour result shows here. It is a checklist, not medical advice.

Keep taking prescribed medicine, and bring the Supplement Facts panel to your clinician. They hold your lab results, which no label can see.

Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee

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If you decide04

What does Sugar Defender cost?

Three bottles cost $207 and six cost $294, with free US shipping on both; two cost $158 plus shipping.

Three Sugar Defender bottles
3 bottles: $207, $69 a bottle, free US shipping
Six Sugar Defender bottles
6 bottles: $294, $49 a bottle, free US shipping

Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee

See packs

FAQ05

Sugar Defender questions people ask

Does green tea extract in a liquid carry the same liver note as capsules?

The source ties reports mainly to extracts in tablet or capsule form (NCCIH, Green Tea). Whether that carries over to a liquid blend with hidden amounts is unknown.

What are the signs a supplement is bothering the liver?

Ask your clinician, since symptoms vary and testing is needed. Do not wait on a label to tell you; report a serious reaction to FDA (FDA, How to Report a Problem with Dietary Supplements).

Why mention the licorice compound for kidney questions?

Glycyrrhizin can affect heart rhythm and is a concern with high blood pressure (NCCIH, Licorice Root). Ask your clinician whether that applies to you.

Who wrote this06

Written and reviewed by

Written byThe Sugar Defender label deskIsugardefender, Sugar Defender U.S. shop

Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.

Medically reviewed byDr. Andres Palacio, MD, PhysicianRole: Medical reviewerReview date: October 19, 2026

Last updated . Read our editorial standards and how we check reviews. This website is run by Isugardefender, a Sugar Defender U.S. shop, not by the manufacturer or the distributor. We earn money when you buy through our order links.

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