Blog
Sugar Defender and Blood Pressure Medication: Licorice, Guarana and More
Sugar Defender and blood pressure medication have not been studied together. Four label lines carry flags: licorice compound and guarana can push pressure up, while forskolin and arginine can push it down. Their amounts are hidden, so no one can predict the net effect. Ask your prescriber or pharmacist before use.
Written by the Sugar Defender label deskUpdated · 4 min read

Short answer01
Is Sugar Defender okay with blood pressure medication?
No one can say. No interaction study of Sugar Defender exists, and the label tells you only to consult your physician if you take other medication.
The useful way to read it is line by line. Four of the 23 lines can nudge blood pressure, and they do not all nudge the same way.
The four flags02
Which ingredients can affect blood pressure?
A licorice compound, guarana, coleus and arginine each carry a blood pressure flag in the sources.
| Label line | At most per mL | Direction and source note |
|---|---|---|
| Guarana seed (3rd) | 67 mg | Up: high doses can raise it; caffeine (MSKCC, Guarana) |
| Coleus root (9th) | 22 mg | Down: forskolin can lower it and add to blood pressure medicine (MSKCC, Forskolin (Coleus forskohlii)) |
| L-arginine (16th) | 12.5 mg | Down: may add to blood pressure medicine (MSKCC, Arginine) |
| Licorice compound (18th) | 11 mg | Up and rhythm: glycyrrhizin can cause irregular heartbeat; people with high blood pressure may be at risk from small amounts (NCCIH, Licorice Root) |
Ceiling = 200 divided by the place number, from the label order. Not a measurement.
Licorice03
Does the licorice compound matter for hypertension?
It is the flag a hypertension patient should read twice, because the source says small amounts can matter in people with high blood pressure (NCCIH, Licorice Root).
The label line is monoammonium glycyrrhizinate, a licorice compound. At most 11 mg per mL fits under the label order, yet the amount itself is hidden.
The same source notes reports of interactions with corticosteroids, a second reason to show the label to a pharmacist.

Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee
See packsNet effect04
Do the pushes cancel out?
Maybe, maybe not, and nobody can calculate it from the label.
Two lines pulling up and two pulling down do not sum to zero. Each acts through a different path, at an unknown amount, in an unknown person. A home cuff log can show what happens to you, if your prescriber wants one.
Do not skip or change a blood pressure dose because of a supplement. Detail on the other herbs sits on the other blend herbs page, the guarana page and the medicines guide.
Where can I order Sugar Defender?
If your prescriber clears it, Sugar Defender sells in three packs on the official order page.

Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee
See packs| Pack | 2 bottles | 3 bottles | 6 bottles |
|---|---|---|---|
| Bottles | 2 | 3 | 6 |
| Total mL (servings) | 120 mL (120) | 180 mL (180) | 360 mL (360) |
| Price per bottle | $79 | $69 | $49 |
| Total | $158 | $207 | $294 |
| Days at the label's 1 mL a day | 120 | 180 | 360 |
| Per day at 1 mL | about $1.32 | about $1.15 | about $0.82 |
| Days as the order page counts | 60 | 90 | 180 |
| Per day on that count | about $2.63 | about $2.30 | about $1.63 |
| Shipping (US) | Added at checkout | Free | Free |
| Digital e-books | None | Two | Two |
| Guarantee | 60 days | 60 days | 60 days |
FAQ05
Sugar Defender questions people ask
Can guarana raise blood pressure?
High doses of guarana can, according to the source, since its caffeine can speed the heart and raise pressure (MSKCC, Guarana). Sugar Defender prints no caffeine amount, so the dose in 1 mL cannot be checked.
Does licorice interact with blood pressure pills?
The source warns people with high blood pressure about glycyrrhizin even in small amounts, and notes reported interactions with corticosteroids (NCCIH, Licorice Root). Ask a pharmacist how that applies to your drugs.
Should I check my blood pressure at home after starting a supplement?
Ask your prescriber. A home log can show a trend, but only a clinician can say what a change means. Do not adjust a dose yourself based on a cuff reading.
Who wrote this06
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by Isugardefender, a Sugar Defender U.S. shop, not by the manufacturer or the distributor. We earn money when you buy through our order links.
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Ready to try Sugar Defender?
Check your medicines first, then pick a pack. Three or six bottles ship free in the US and cost less per bottle, and every pack carries the 60-day money-back guarantee.
- Secure checkout on the order page
- 60-day money-back guarantee
- Ships from the U.S.; free on 3 or 6


