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Raspberry Ketones: How Strong Is the Evidence?

Quick answer

The raspberry ketones evidence is weak. Most research is in animals and cells, and the only human studies used multi-ingredient products, so no benefit can be pinned on raspberry ketone alone (OPSS (DoD), Raspberry Ketone). In Sugar Defender it sits 13th of 22 blend lines, which caps it at about 15 mg per mL.

Written by the Sugar Defender label deskUpdated · 4 min read

The flat Sugar Defender label with directions, brand panel and Supplement Facts
The label, laid flat. Raspberry ketones are the 13th of 22 lines in the blend, so the amount per mL is hidden.

The research01

How strong is the raspberry ketones evidence?

Weak. Memorial Sloan Kettering reports that most raspberry ketone research is in animals and cells (OPSS (DoD), Raspberry Ketone).

The few human studies used products that mixed several ingredients. When caffeine, capsaicin or other compounds are in the same capsule, nobody can credit the raspberry ketone (OPSS (DoD), Raspberry Ketone).

The claim02

Do raspberry ketones help with weight loss?

No evidence shows that raspberry ketone supplements are safe or effective for weight loss (OPSS (DoD), Raspberry Ketone). Sugar Defender's sales page does not make this claim for raspberry ketones by name, but it leans on "natural weight loss" language elsewhere.

The FTC expects health claims to rest on human trials of the same product, dose and group of people (FTC, Health Products Compliance Guidance). Animal results and testimonials do not meet that bar. The table checks other sales lines the same way.

  1. Sales headline“The #1 Rated Blood Sugar Formula”No ranking source, rating body or trial is named. No trial has tested Sugar Defender. (Sugar Defender sales page) (FTC, Health Products Compliance Guidance)
  2. Ingredient count“24 proven ingredients”The page then names 8. The label has 23 lines: chromium plus a 22-ingredient blend, with only one amount printed. (Sugar Defender sales page) (21 CFR 101.36 (eCFR))
  3. Science headline“New Breakthrough in Blood Sugar Science”No published study of the drops is cited. NCCIH finds little evidence that supplements help diabetes. (NCCIH, Diabetes and Dietary Supplements) (FTC, Health Products Compliance Guidance)
  4. PromiseSupports healthy glucose levels and “natural weight loss”No product trial. The weight-loss ingredients (African mango, forskolin, raspberry ketone, capsaicin) have weak or no evidence alone. (NIH ODS, Dietary Supplements for Weight Loss) (ADA, Vitamins & Supplements)
  5. Chromium copyChromium “Reduces Obesity & Lowers Blood Pressure”Glucose studies used 200-1,000 mcg a day with mixed results. One dropper has 0.7 mcg. (NIH ODS, Chromium)
  6. Bonus titleAn e-book called “Learn How to Manage Type II Diabetes”A book title, not a property of the drops. No supplement treats diabetes; care stays with your doctor. (NCCIH, Diabetes and Dietary Supplements) (FDA, Illegally Sold Diabetes Treatments)
  7. Popularity line“96% Of Customers Order 6 Bottles”No source or sample size is given, so it cannot be checked. (FTC, How To Evaluate Online Reviews)
  8. Bottle band“Blood Sugar Support Formula” with the FDA statementStructure/function wording, allowed with the FDA statement. It is not a disease claim. (FDA, Using Dietary Supplements)

Claims as printed on the sales page (Sugar Defender sales page) and the label. Health claims need competent and reliable scientific evidence, generally human trials of the same product (FTC, Health Products Compliance Guidance).

Dose03

How much raspberry ketone does Sugar Defender hold?

The label does not say. Raspberry ketones hold 13th place in a 200 mg blend, so one mL carries at most about 15 mg.

Supplement doses against the label ceiling
ItemPer day
Supplement doses cited100-1,400 mg (OPSS (DoD), Raspberry Ketone)
Sugar Defender, 1 mL, ceilingAbout 15 mg
Printed amountNot published

The ceiling is 200 divided by 13, from the descending order that blend rules require (21 CFR 101.36 (eCFR)). Even the maximum sits below the low end of that range.

Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee

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Safety04

What are the raspberry ketone side effects?

There is no proof of safety to lean on. The same review notes that supplement doses far exceed what people eat in food (OPSS (DoD), Raspberry Ketone).

So the label's advice stands: adults who take other medication, or who are pregnant or nursing, should consult a physician first. Keep taking prescribed medicine.

See the other blend herbs page for the rest of the list.

If you try it05

What are the Sugar Defender pack prices?

Three bottles are $207 and six are $294, with free US shipping and a 60-day money-back guarantee on official orders.

Three Sugar Defender bottles
3 bottles: $207, $69 a bottle, free US shipping
Six Sugar Defender bottles
6 bottles: $294, $49 a bottle, free US shipping

Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee

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FAQ06

Sugar Defender questions people ask

Are raspberry ketones the same as raspberry extract?

No. Raspberry ketone is a single compound, and the label here lists raspberry ketones, not a whole-fruit extract. The research we cite concerns the ketone (OPSS (DoD), Raspberry Ketone).

Can raspberry ketones hurt you?

Harm is possible, and no evidence shows they are safe. Supplement doses of 100 to 1,400 mg a day far exceed normal dietary intake (OPSS (DoD), Raspberry Ketone).

Is the raspberry ketone dose on the label?

No. It is hidden inside the 200 mg blend. The 13th-place order caps it at about 15 mg per mL.

Who wrote this07

Written and reviewed by

Written byThe Sugar Defender label deskIsugardefender, Sugar Defender U.S. shop

Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.

Medically reviewed byDr. Andres Palacio, MD, PhysicianRole: Medical reviewerReview date: October 19, 2026

Last updated . Read our editorial standards and how we check reviews. This website is run by Isugardefender, a Sugar Defender U.S. shop, not by the manufacturer or the distributor. We earn money when you buy through our order links.

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