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Monoammonium Glycyrrhizinate: The Licorice Ingredient in Sugar Defender

Quick answer

Monoammonium glycyrrhizinate is a licorice compound, listed 18th of 22 lines in Sugar Defender's 200 mg blend. Its amount is not printed, but the label order caps it at about 11 mg per mL. Glycyrrhizin can affect heartbeat and blood pressure, so people with high blood pressure should ask a doctor first (NCCIH, Licorice Root).

Written by the Sugar Defender label deskUpdated · 4 min read

Two Sugar Defender dropper bottles side by side
Two bottles. The licorice compound is the 18th of 22 lines in the blend, with no printed amount.

The ingredient01

What is monoammonium glycyrrhizinate?

Monoammonium glycyrrhizinate is an ammonium salt of glycyrrhizin, the main sweet-tasting compound from licorice root. On Sugar Defender's label it appears as a plain line, with no plant name beside it.

The label groups it with raspberry ketones as an "other compound" rather than a plant extract. We did not review other glycyrrhizin salts, such as the potassium ones, so what follows applies to glycyrrhizin in general (NCCIH, Licorice Root).

The math02

How much licorice compound is in one mL?

Not more than about 11 mg, and the maker does not say. Position 18 caps it at 200 divided by 18, because each line weighs no more than the one before it (21 CFR 101.36 (eCFR)).

What the 200 mg blend allows for the licorice compound
MeasurePer 1 mL
Blend total, 22 lines200 mg
Even splitAbout 9 mg
Ceiling in 18th placeAbout 11 mg
Printed amountNot published

The true figure may be much lower. Seventeen lines sit above it, and four sit below.

Safety03

Is glycyrrhizin safe?

For many adults in small amounts, probably yes, but the caution list is real. Glycyrrhizin can cause irregular heartbeat, mostly with large or long-term use, and people with high blood pressure may be at risk even from small amounts (NCCIH, Licorice Root).

Large amounts of licorice are unsafe in pregnancy, and interactions with corticosteroids have been reported (NCCIH, Licorice Root). The label already tells pregnant or nursing women and anyone on other medication to consult a physician.

Keep taking prescribed medicine

Do not stop or change a blood pressure or other medicine because of a supplement. Tell your care team what you take.

Report problems to FDA if they follow a supplement (FDA, How to Report a Problem with Dietary Supplements). Our side effects page lists the other flags in this formula.

Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee

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Purpose04

Why would a supplement include a licorice sweetener?

The label does not say. Taste is one guess, but stevia and xylitol are already listed as the sweeteners in the liquid.

The sales page makes no claim for this line, and we found no study of glycyrrhizinate for blood sugar. Treat it as a line to check against your blood pressure history, not as a benefit.

The other blend herbs page covers its neighbors.

If you try it05

What does Sugar Defender cost?

Two bottles cost $158 plus shipping, three cost $207 and six cost $294, with free US shipping on the larger packs.

Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee

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Sugar Defender packs on the sales page, October 18, 2026.
Pack2 bottles3 bottles6 bottles
Bottles236
Total mL (servings)120 mL (120)180 mL (180)360 mL (360)
Price per bottle$79$69$49
Total$158$207$294
Days at the label's 1 mL a day120180360
Per day at 1 mLabout $1.32about $1.15about $0.82
Days as the order page counts6090180
Per day on that countabout $2.63about $2.30about $1.63
Shipping (US)Added at checkoutFreeFree
Digital e-booksNoneTwoTwo
Guarantee60 days60 days60 days
Two Sugar Defender bottles
2 bottles: $158 plus shipping, $79 a bottle

FAQ06

Sugar Defender questions people ask

Is licorice root safe with high blood pressure?

Not always. Glycyrrhizin from licorice can affect heartbeat, and people with high blood pressure may be at risk even from small amounts (NCCIH, Licorice Root). Ask a doctor first.

Can you take licorice compounds while pregnant?

Large amounts of licorice are unsafe in pregnancy (NCCIH, Licorice Root). The Sugar Defender label asks pregnant or nursing women to consult a physician before use.

Does glycyrrhizinate interact with steroids?

Interactions with corticosteroids have been reported for glycyrrhizin (NCCIH, Licorice Root). Tell your prescriber about every supplement you use.

Who wrote this07

Written and reviewed by

Written byThe Sugar Defender label deskIsugardefender, Sugar Defender U.S. shop

Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.

Medically reviewed byDr. Andres Palacio, MD, PhysicianRole: Medical reviewerReview date: October 19, 2026

Last updated . Read our editorial standards and how we check reviews. This website is run by Isugardefender, a Sugar Defender U.S. shop, not by the manufacturer or the distributor. We earn money when you buy through our order links.

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