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Grape Seed Extract and Blood Sugar: What We Know
Grape seed extract blood sugar evidence is thin. Grape seed is second in the Sugar Defender blend, so one mL holds at most 100 mg. Reviews of small studies point to modest effects on cholesterol, triglycerides and diastolic blood pressure, not on glucose, and none are definitive.
Written by the Sugar Defender label deskUpdated · 4 min read
On the label01
Where is grape seed in Sugar Defender?
Grape seed is the second line of the 22-ingredient blend, so only maca root can weigh more.
It could be the second-largest ingredient in the dropper. The label gives no amount, though, so the only firm number is a ceiling: 200 divided by 2, or 100 mg per mL. An even split is about 9 mg.
The label spells the plant "Vitis finifera", a misprint for vinifera. It also does not state how much of the extract is OPC, the antioxidant compounds grape seed is known for.
The research02
Does grape seed extract help with blood sugar?
The sources we cite do not show that it does. Memorial Sloan Kettering describes reviews of small studies pointing to possible modest effects on LDL cholesterol, triglycerides and diastolic blood pressure (NCCIH, Grape Seed Extract).
Those findings are not definitive, and glucose is not on that list. So grape seed extract benefits, as measured, sit mostly in heart-related numbers.
| Question | Answer |
|---|---|
| Blend place | 2nd of 22 |
| Most per mL | 100 mg |
| Studied for | LDL, triglycerides, diastolic pressure |
| Safety | Generally well tolerated |
Sales page03
What does the sales page say about grape seed?
It says nothing. Grape seed is not among the eight ingredients with a printed promise. Here are the claims it does make.
- Sales headline“The #1 Rated Blood Sugar Formula”No ranking source, rating body or trial is named. No trial has tested Sugar Defender. (Sugar Defender sales page) (FTC, Health Products Compliance Guidance)
- Ingredient count“24 proven ingredients”The page then names 8. The label has 23 lines: chromium plus a 22-ingredient blend, with only one amount printed. (Sugar Defender sales page) (21 CFR 101.36 (eCFR))
- Science headline“New Breakthrough in Blood Sugar Science”No published study of the drops is cited. NCCIH finds little evidence that supplements help diabetes. (NCCIH, Diabetes and Dietary Supplements) (FTC, Health Products Compliance Guidance)
- PromiseSupports healthy glucose levels and “natural weight loss”No product trial. The weight-loss ingredients (African mango, forskolin, raspberry ketone, capsaicin) have weak or no evidence alone. (NIH ODS, Dietary Supplements for Weight Loss) (ADA, Vitamins & Supplements)
- Chromium copyChromium “Reduces Obesity & Lowers Blood Pressure”Glucose studies used 200-1,000 mcg a day with mixed results. One dropper has 0.7 mcg. (NIH ODS, Chromium)
- Bonus titleAn e-book called “Learn How to Manage Type II Diabetes”A book title, not a property of the drops. No supplement treats diabetes; care stays with your doctor. (NCCIH, Diabetes and Dietary Supplements) (FDA, Illegally Sold Diabetes Treatments)
- Popularity line“96% Of Customers Order 6 Bottles”No source or sample size is given, so it cannot be checked. (FTC, How To Evaluate Online Reviews)
- Bottle band“Blood Sugar Support Formula” with the FDA statementStructure/function wording, allowed with the FDA statement. It is not a disease claim. (FDA, Using Dietary Supplements)
Claims as printed on the sales page (Sugar Defender sales page) and the label. Health claims need competent and reliable scientific evidence, generally human trials of the same product (FTC, Health Products Compliance Guidance).
Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee
See packsCautions04
Is grape seed extract safe?
Grape seed extract is generally well tolerated, but little is known about its safety in pregnancy or breastfeeding (NCCIH, Grape Seed Extract).
If you take a blood pressure medicine, ask your prescriber before adding any supplement that lists it, since the studies touched on diastolic pressure. Keep taking prescribed medicine.
Do not confuse it with grapefruit seed extract, which is the eleventh line and a different plant.
If you try it05
What does Sugar Defender cost?
Two bottles cost $158 plus shipping. Three bottles are $207 and six are $294, both with free US shipping.
Sugar Defender: from $49 a bottle60 mL · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day money-back guarantee
See packsThe remaining plants are listed on the other blend herbs page, and every line is on the ingredients page.
FAQ06
Sugar Defender questions people ask
What is OPC in grape seed extract?
OPC stands for oligomeric proanthocyanidins, the antioxidant compounds in the seed. The Sugar Defender label does not say how much of its grape seed extract is OPC.
Can grape seed extract affect blood pressure?
Reviews of small studies point to a possible modest effect on diastolic pressure, though not a definitive one. Ask your prescriber if you take pressure medicine (NCCIH, Grape Seed Extract).
Is the grape seed in Sugar Defender a big dose?
It may be the second-largest ingredient, but the most it can hold is 100 mg per mL. The label prints no actual amount.
Who wrote this07
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by Isugardefender, a Sugar Defender U.S. shop, not by the manufacturer or the distributor. We earn money when you buy through our order links.
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